Time Series Proteome Profiling To Study Endoplasmic Reticulum Stress Response
نویسندگان
چکیده
منابع مشابه
Cancer Microenvironment and Endoplasmic Reticulum Stress Response
Different stressful conditions such as hypoxia, nutrient deprivation, pH changes, or reduced vascularization, potentially able to act as growth-limiting factors for tumor cells, activate the unfolded protein response (UPR). UPR is therefore involved in tumor growth and adaptation to severe environments and is generally cytoprotective in cancer. The present review describes the molecular mechani...
متن کاملEndoplasmic reticulum stress response and transcriptional reprogramming
Endoplasmic reticulum (ER) is an intracellular organelle responsible for protein folding and assembly, lipid and sterol biosynthesis, and calcium storage. As a protein folding compartment, the ER provides a high-fidelity quality control system to ensure that only correctly folded proteins are released from the ER and that unfolded and/or misfolded proteins are retained and degraded. A number of...
متن کاملEndoplasmic Reticulum Stress Response in Arabidopsis Roots
Roots are the frontier of plant body to perceive underground environmental change. Endoplasmic reticulum (ER) stress response represents circumvention of cellular stress caused by various environmental changes; however, a limited number of studies are available on the ER stress responses in roots. Here, we report the tunicamycin (TM) -induced ER stress response in Arabidopsis roots by monitorin...
متن کاملOxidative stress contributes to autophagy induction in response to endoplasmic reticulum stress in Chlamydomonas reinhardtii.
The accumulation of unfolded/misfolded proteins in the endoplasmic reticulum (ER) results in the activation of stress responses, such as the unfolded protein response or the catabolic process of autophagy to ultimately recover cellular homeostasis. ER stress also promotes the production of reactive oxygen species, which play an important role in autophagy regulation. However, it remains unknown...
متن کاملOxidative Stress Contributes to Autophagy Induction in Response to Endoplasmic Reticulum Stress in Chlamydomonas reinhardtii1[W]
Instituto de Bioquímica Vegetal y Fotosíntesis, Consejo Superior de Investigaciones Científicas-Universidad de Sevilla, 41092 Seville, Spain (M.P.-M., J.L.C.); and Centre National de la Recherche Scientifique (M.E.P.-P.; S.D.L.) and Sorbonne Universités, Université Pierre et Marie Curie, University of Paris 06 (M.E.P.-P.; S.D.L.), Unité Mixte de Recherche 8226, Laboratoire de Biologie Moléculai...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2008
ISSN: 1535-3893,1535-3907
DOI: 10.1021/pr700842m